D48.5 ICD-10-CM Code: Neoplasm of uncertain behavior of skin

D48.5 is the billable ICD-10-CM code for “Neoplasm of uncertain behavior of skin” in the FY 2027 U.S. code set, effective Oct 1, 2026.

Official description

D48.5

Neoplasm of uncertain behavior of skin

ICD-10-CM diagnosis code · United States clinical modification

Where D48.5 sits

  1. 1

    Chapter 2

    Neoplasms (C00-D49)

  2. 2

    Section

    Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)

  3. 3

    Category D48

    Neoplasm of uncertain behavior of other and unspecified sites

  4. 4

    Code D48.5

    Neoplasm of uncertain behavior of skin

Notes for this code

Inclusion terms

  • Neoplasm of uncertain behavior of anal margin
  • Neoplasm of uncertain behavior of anal skin
  • Neoplasm of uncertain behavior of perianal skin
  • Neoplasm of uncertain behavior of skin of breast

Code first

No “code first” instruction is listed for D48.5.

Use additional code

No “use additional code” instruction is listed for D48.5.

Excludes1

Conditions that should not be reported together with this code.

  • neoplasm of uncertain behavior of anus NOS (D37.8)
  • neoplasm of uncertain behavior of skin of genital organs (D39.8, D40.8)
  • neoplasm of uncertain behavior of vermilion border of lip (D37.0)

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for D48.5.

Source and release

Data release
U.S. ICD-10-CM · FY 2027
Effective date
Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Frequently asked questions

What does ICD-10-CM code D48.5 mean?

D48.5 is the FY 2027 U.S. ICD-10-CM code for “Neoplasm of uncertain behavior of skin.”

Is D48.5 a billable or specific ICD-10-CM code?

Yes. In the FY 2027 reference data used on this page, D48.5 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.

Where is D48.5 located in ICD-10-CM?

D48.5 is listed in Chapter 2, Neoplasms (C00-D49), within Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48) (D37–D48), under category D48, Neoplasm of uncertain behavior of other and unspecified sites.

What coding notes are listed for D48.5?

Its listed inclusion terms are Neoplasm of uncertain behavior of anal margin; Neoplasm of uncertain behavior of anal skin; Neoplasm of uncertain behavior of perianal skin; Neoplasm of uncertain behavior of skin of breast. No code-first instruction is listed. Excludes1 notes: neoplasm of uncertain behavior of anus NOS (D37.8); neoplasm of uncertain behavior of skin of genital organs (D39.8, D40.8); neoplasm of uncertain behavior of vermilion border of lip (D37.0). No Excludes2 note is listed.