CLINICAL EVIDENCE APPRAISAL RECORD
Reader / appraisal date:
Clinical question: population, intervention or exposure, comparison,
outcome and follow-up period:
Decision this evidence could inform:

SOURCE AND DESIGN
Citation / DOI or URL / publication date / version:
Study design / setting / recruitment dates:
For a review: last search date, included designs and relevant studies:
Protocol or registration / funding and disclosed interests:

RESULT FOR ONE OUTCOME
Outcome definition / how and when measured:
Number allocated or enrolled / number analysed / missing outcomes:
Events and denominators by group, or other reported summary:
Effect measure / estimate / confidence interval / time horizon:
Absolute effect and baseline risk used, if calculated:
Harms / burdens reported / outcomes not measured:

APPRAISAL
Design-specific appraisal tool and version, if used:
Potential bias / evidence in methods, results or protocol / page or table:
Effect of missing data, measurement or selective reporting:
For a body of evidence: consistency, precision, directness and missing studies:
Published certainty judgment / outcome / supporting explanation:

APPLICABILITY AND NEXT STEP
Important differences from the intended population, intervention and setting:
Resources and follow-up needed / patient priorities relevant to the decision:
Conclusion supported by this evidence:
Unanswered question / further source or specialist input needed:
Decision owner / next review date / what would change the conclusion: